This psalm, says Fr. Patrick, is best seen in the context of Christ's trial before Pilate. Most important to remember, however, is that in verses like vv. 37-42--
"37 I have pursued my enemies and overtaken them; Neither did I turn back again till they were destroyed.
38 I have wounded them, So that they could not rise; They have fallen under my feet.
39 For You have armed me with strength for the battle; You have subdued under me those who rose up against me.
40 You have also given me the necks of my enemies, So that I destroyed those who hated me.
41 They cried out, but there was none to save; Even to the LORD, but He did not answer them.
42 Then I beat them as fine as the dust before the wind; I cast them out like dirt in the streets."
--we must remind ourselves of who "the real villians in this psalm" are: "the satanic spirits, the true enemies who consipred against the Holy and Righteous One. Consequently, it is the fallen angels that we should see referenced in so many lines of this psalm" instead of the Jews or the Romans, "for against them [the spirits] our Lord waged a combat without quarter."